Lufenuron is an insect development inhibitor from the benzoylphenyl urea class. It is active against fleas that have fed on treated cats and dogs and are exposed to lufenuron in the host’s blood.
CAS No.: 103055-07-8
Molecular Formula: C17H8Cl2F8N2O3
Molecular Weight: 511.15
Melting point |
174.1 °C |
Density |
1.631 ± 0.06 g/cm3 (Predicted) |
Vapor pressure |
<0.4 x10-3 Pa (25 °C) |
Flash point |
170 °C |
Storage temperature |
0–6 °C |
Solubility |
100 mg/L in organic solvents at 20 °C |
Form |
Solid |
pKa |
8.49 ± 0.46 (Predicted) |
Water solubility |
<0.06 mg/L (25 °C) |
Color |
Off-white to light yellow |
Symbol (GHS) |
|
Signal word |
Warning |
Hazard codes |
Xi; N, N; Xi |
RIDADR |
3077 |
WGK Germany |
2 |
Hazard class |
9 |
Packing group |
III |
HS Code |
29242990 |
Description
Lufenuron is an insect development inhibitor of the benzoylphenyl urea class. It is active against fleas that have fed on treated cats and dogs and become exposed to lufenuron through the host’s blood. Lufenuron also acts via its presence in adult flea feces, which leads to ingestion by flea larvae. These two activities result in the production of eggs that are unable to hatch, thereby significantly reducing flea larvae populations. Due to its lipophilicity, lufenuron deposits in the animals’ adipose tissues and is slowly released into the bloodstream. This helps maintain effective blood concentrations over the recommended oral dosing interval of 1 month.
Uses
Lufenuron is used for the control of Lepidoptera and Coleoptera larvae on cotton, maize and vegetables, and for control of citrus whitefly and rust mites on citrus fruit. It is also used to control fleas on pets and cockroaches in houses. Lufenuron is approved for use in dogs and cats aged 6 weeks and older for controlling flea populations.